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Disposition of Toxic Drugs and Chemicals in Man, by Randall C. Baselt
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Eighth Edition Randall C. Baselt, Ph.D. The purpose of this work is to present in a single convenient source the current essential information on the disposition of the chemicals and drugs most frequently encountered in episodes of human poisoning. The data included relate to the body fluid concentrations of substances in normal or therapeutic situations, concentrations in fluids and tissues in instances of toxicity and the known metabolic fate of these substances in man. Brief mention is made of specific analytical procedures that are applicable to the determination of each substance and its active metabolites in biological specimens. It is expected that such information will be of particular interest and use to toxicologists, pharmacologists, clinical chemists and clinicians who have need either to conduct an analytical search for these materials in specimens of human origin or to interpret analytical data resulting from such a search.
- Sales Rank: #3066340 in Books
- Published on: 2008-08-01
- Original language: English
- Number of items: 1
- Dimensions: 2.90" h x 7.30" w x 10.30" l, 5.61 pounds
- Binding: Hardcover
- 1717 pages
Most helpful customer reviews
3 of 3 people found the following review helpful.
An invaluable resource
By Dr. Robert J. Flanagan
The fact that this volume is in its 8th Edition (edition 1 appeared in 1978) testifies to its worth to the community it serves. Should institutions purchase this book if they have the previous edition? The answer of course has to be `yes'. There are 957 entries (1717 pages), 222 compounds having been added since 2004. It is an indispensable source of practically-useful information on drug/poison pharmacokinetics, metabolism, toxicology, and analytical methodology for case work and teaching/research alike. A very welcome feature is that `old' compounds are not simply deleted - in toxicology poisons never simply fade away, they just crop up when you least expect them!
A note of caution. Proper interpretation of analytical data requires not only an understanding of the circumstances surrounding a case, but also an appreciation of the circumstances under which any data cited to aid interpretation were produced. Hence the value of the references to the primary literature that make up a substantial proportion of the book.
3 of 3 people found the following review helpful.
Baselt's 2008 edition
By Robert M. Julien
The book is an essential for anyone performing toxicology consultations.
My only big complaint is that Amazon.com charged more than $70.00 over the direct purchase price from the book seller. Next time I want textbooks via the net, I will skip Amazon and go direct. Amazon should refund some of this overcharge.
0 of 0 people found the following review helpful.
Five Stars
By Nagarajarao Shamaladevi
Excellent book to refer
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